p16INK4astatus
    Score 0 Score 1 Score 2 Score 3
n=91   42 12 8 29
Age (mean±S.D) 75.3 ± 8.7        
Gender          
Male 72 29 11 6 26
Female 19 13 1 2 3
Tumor grade          
Low 54 32 5 3 14
High 37 10 7 5 15
Tumor invasion          
noninvasive 74 38 7 7 22
invasive 17 4 5 1 7
           
original 61 24 7 5 25
recurrence 30 18 5 3 4
Score 0, no staining; Score1, <20%; Score2, 21%–70%; Score3, >71%
Table 1: Clinicopathological characteristics of the patients and correlation with p16INK4a immunophenotype.