| |
Fasting blood glucose |
Fasting serum insulin |
Β-cell function |
| Group |
(mmol/l) |
(pmol/l) |
( %) |
| |
Day 1 |
Day 29 |
Day 1 |
Day 29 |
Day 1 |
Day 29 |
Diabetic
(n=9) |
9.65 ± 1.04 |
11.06 ± 1.22 |
39.05 ± 2.25 |
34.87 ± 2.48 |
24.8 ± 2.7 |
19.7± 3.9 |
GS-treated
(n=11) |
10.13 ± 1.02 |
7.24 ± 0.33* |
37.64 ± 2.35 |
72.19 ± 5.35* |
21.5 ± 3.6 |
63.4± 7.5* |
GB-treated
(n=8) |
9.02 ± 0.53 |
5.75 ± 0.53* |
41.17 ± 3.58 |
83.74 ± 6.72* |
28.6 ± 2.7 |
108.5± 8.7* |
| All values were expressed as mean ± SEM. n=number of rats; GS:Gymnemasylvestre; GB: Glibenclamide. *p<0.001, versus diabetic group. |
|
