Differentiation Nucleus N/C ratio Cytoplasm Neurophils Rosette forming MKI
Shape Size Chromatin
Undifferentiated Round Small Prominent hyperchromatism Very high Scant Seldom seen Absence high
Poorly differentiated Round to oval Small to midium Hyperchromatism High Little Seen in background Presence low
Differentiating Round to oval Small, large Hyperchromatism Low Abundant Relatively abundant Occasionally presence -
Table 5: Comparison of cytological findings of neuroblastomas.