Histological type Radius of long axis (μm) Area (μm) Perimeter (μm) Roundness Linear factor Average ± SD Average ± SD Average ± SD Average ± SD Average ± SD Neuroblastic cells UNB 4.34 ± 0.75 327.07 ± 110.39 26.64 ± 4.49 0.903 ±   0.02* 1.162 ±   0.11† PNB 4.59 ± 1.18 349.62 ± 181.55 27.62 ± 6.62 0.881 ± 0.04* 1.243 ± 0.20† Ganglion like cells DNB 8.54 ±   1.16† 916.23 ± 138.62 47.82 ±   † 3.99† 0.804 ± 0.07 1.603 ± 0.41 GNB 7.42 ± 0.95† 791.66 ± 247.52 42.69 ± 5.88† 0.851 ± 0.05 1.432 ± 0.29

UNB: Neuroblastoma undifferentiated, PNB: Neuroblastoma poorly differentiated, DNB: Neuroblastoma differentiating, GNB: Ganglioneuroblastoma. *p < 0.0001, †p< 0.05; significant, Mann-Whitney U-test. Table 7: The Correlation between Nuclear Morphological image analysis in Neuroblastic tumor.