Substance administered Dose (mg/kg) Liver parameters
ALP(U/L) ALT (U/L) AST (U/L) GGT (U/L)
AQ crude 250 168.03 ± 10.79 62.88 ± 3.65 162.57 ± 10.85 2.80 ± 0.21
500 211.57 ± 10.85 77.87 ± 6.01 238.58 ± 42.96 3.06 ±0.43
1000 239.33 ± 8.43 80.50 ± 0.99 246.78± 14.08 3.58 ± 0.15
70% EtOH crude 250 179.18 ± 7.92 63.75 ± 3.55 176.15 ± 12.81 2.55 ± 0.18
500 219.57 ± 15.24 64.10 ± 2.39 193.73 ± 27.64 2.71 ±0.35
1000 227.08 ± 15.62 66.67 ± 1.54 214.15 ± 9.84 3.31 ±0.18
EtAc fraction of AQ crude 250 195.47 ± 11.59 65.03 ± 3.25 199.47 ± 35.39 2.8500 ± 0.56
500 204.93 ± 25.91 65.93 ± 2.38 244.32 ± 20.88 3.5500 ± 0.49
1000 222.02 ± 11.19 68.13 ± 1.17 251.33 ± 7.37 4.3000 ± 0.61
AQ residue of AQ crude 250 193.23 ± 13.29 57.18 ± 2.02 188.57 ± 19.75 3.1333 ± 0.17
500 215.67 ± 4.11 64.20 ± 0.91 196.73 ± 5.55 3.5333 ± 0.39
1000 237.53 ± 18.38 65.23 ± 3.02 200.27 ± 25.00 3.7500 ± 0.29
Distill.water ad libitum 174.47 ± 8.64 66.63 ± 3.54 194.75 ± 18.18 3.9667 ±1.16
Table 1: Effect of crude extracts and fractions of M. stenopetala on liver of rats (Results are expressed as mean ± SEM (n = 6), * = Compared to normal control; 1 = P < 0.05; 2 = P < 0.01; 3 = P < 0.001)