Substance administered
Dose (mg/kg)
Liver parameters
ALP(U/L)
ALT (U/L)
AST (U/L)
GGT (U/L)
AQ crude
250
168.03 ± 10.79
62.88 ± 3.65
162.57 ± 10.85
2.80 ± 0.21
500
211.57 ± 10.85
77.87 ± 6.01
238.58 ± 42.96
3.06 ±0.43
1000
239.33 ± 8.43
80.50 ± 0.99
246.78± 14.08
3.58 ± 0.15
70% EtOH crude
250
179.18 ± 7.92
63.75 ± 3.55
176.15 ± 12.81
2.55 ± 0.18
500
219.57 ± 15.24
64.10 ± 2.39
193.73 ± 27.64
2.71 ±0.35
1000
227.08 ± 15.62
66.67 ± 1.54
214.15 ± 9.84
3.31 ±0.18
EtAc fraction of AQ crude
250
195.47 ± 11.59
65.03 ± 3.25
199.47 ± 35.39
2.8500 ± 0.56
500
204.93 ± 25.91
65.93 ± 2.38
244.32 ± 20.88
3.5500 ± 0.49
1000
222.02 ± 11.19
68.13 ± 1.17
251.33 ± 7.37
4.3000 ± 0.61
AQ residue of AQ crude
250
193.23 ± 13.29
57.18 ± 2.02
188.57 ± 19.75
3.1333 ± 0.17
500
215.67 ± 4.11
64.20 ± 0.91
196.73 ± 5.55
3.5333 ± 0.39
1000
237.53 ± 18.38
65.23 ± 3.02
200.27 ± 25.00
3.7500 ± 0.29
Distill.water
ad libitum
174.47 ± 8.64
66.63 ± 3.54
194.75 ± 18.18
3.9667 ±1.16
Table 1:
Effect of crude extracts and fractions of M. stenopetala on liver of rats (Results are expressed as mean ± SEM (n = 6), * = Compared to normal control; 1 = P < 0.05; 2 = P < 0.01; 3 = P < 0.001)