Substance administered Dose (mg/kg) Kidney parameters Creatinine (mg/dl) BUN (mg/dl) AQ crude 250 0.39 ± 0.02*2 19.60 ± 1.01*3 500 0.34 ± 0.01 22.03 ± 1.44*3 1000 0.32 ± 0.00 23.33 ± 0.42*2 70% EtOH crude 250 0.30 ± 0.01 24.00 ± 0.81*1 500 0.32 ± 0.01 22.55 ± 1.76*2 1000 0.34 ± 0.02 21.15 ± 0.73*3 EtAc fraction of AQ crude 250 0.39 ± 0.01 21.81 ± 1.39*3 500 0.35 ± 0.01 18.56 ± 0.73*3 1000 0.32 ± 0.00 24.48 ± 0.44*1 AQ residue of AQ crude 250 0.40 ± 0.01 17.83 ± 0.89*3 500 0.30 ± 0.01 18.06 ± 1.21*3 1000 0.34 ± 0.01 22.33 ± 0.80*3 Distill.water ad libitum 0.33 ± 0.00 29.80 ± 0.92

Table 2: Effect of crude extracts and fractions of M. stenopetala on kidney of rats (Results are expressed as mean ± SEM (n = 6), *= Compared to normal control; 1 = P < 0.05; 2 = P < 0.01; 3 = P < 0.001)