| AgNOR staining |
< 100 intact cells for investigation |
| Ultrasonography |
Cystic component > 5% at any time |
| |
Nodule in direct contact with an adjacent nodule |
| Scintigraphy |
Autonomously functioning nodule in the thyroid at initial investigation |
| Laboratory |
TSH > 4 mU/L at any time |
| |
TSH < 0.2 mU/L at any time |
| |
aTPO> 100 U/L |
| Medication |
Thyrostatic and/or thyroid hormone and/or iodine containing drug at any time |
| Cytology |
Suspicious or malignant and not operated on |
| |
Lymphocytic thyroiditis |
| Histology |
Malignant or diffuse lymphocyticthyroiditis |
| Follow-up period |
< 10.years in non-operated patients |
| |
<6 years in operated patients |
