Figure 4:The experimental Cells ultrastructure, Representative images (3500X). A. The ultrastructure of BEAS-2B cells. B. The ultrastructure of the 5th passages BEASNNK-2B cells. C. The ultrastructure of the 15th passages BEASNNK-2B cells, BEAS-2BNNK Cells enlargement, nuclear gradual deformation and fragmentation, nucleus malformation, organelle enlargement and number increased. D. The ultrastructure of the 25th passages BEASNNK- 2B cells, BEAS-2BNNK Cells appeared multiple nucleoli, and had the obvious characteristics of cancer cells.