Parameters Control subgroups Group II Group III Group IV
  i ii iii iv V  
P53 (mean number of cells/field) 1.7 ±0.48NS 1.9±0.316 NS 1.8±0.426 NS 1.9 ±0.567 NS 2 ±0.471 NS 53.8±10.77aP 2.9±0.57 bP 3.30±0.48bP
iNOS (optical density) 0.0738±0.0181 NS 0.0795±0.0107 NS .0771±0.0151 NS 0.0836±0.0136 NS 0.0693±0.0122 NS 6.451±1.098 aP 0.104±0.028bP 0.107±0.019bP
iNOS (Area %) 1.425±0.318 NS 1.287±0.313 NS 1.286±0.225NS 1.2990± 0.272 NS 1.2230±0.220 NS 89.608±6.11 aP 1.555±0.242 bP 1.636±0.234 bP
Data is expressed as mean ± standard deviation,NS= non-significant difference between control subgroups tested by one-way ANOVA followed by Post Hoc Tukey’s test.P. value = probability of chance, P< 0.05 is significant tested by Student “t” test.aP = 0.001 vs control subgroup i;bP<0.01vs group II.
Table 2: The mean number of p53 positive cells, the mean of iNOS optical density and the mean area percentage of iNOS in the different groups studied.