Figure 4: MMP-2, MMP 9, MMP 14, TIM-1 and TIMP 2 expressions in Cervical Neoplasia MMP- Metalloproteinases, TIMP- Tissue inhibitors of metalloproteinases, CIN – Cervical Intraepithelial Neoplasia, IC – Invasive carcinoma, Group 1-G1, Group-G2, Group 3-G3, Min-Minimum, Max- Maximum, Q1- 25th percentile, Q3-75th percentile. Higher percentages of stromal and tumoral cells expressing MMP 2 were observed in invasive carcinoma (Group 3). Higher percentages of stromal cells expressing MMP-2 were detected in CIN 3 of Group 2 when compared with CIN 3 of Group 1. There was a significantly higher percentage of tumor cells expressing TIMP-1 than stromal cells, when CIN 3 of Group 1 was compared to invasive carcinoma of Group 3. There was a significantly higher percentage of stromal cells expressing TIMP-1 than tumor cells, when invasive carcinoma of Group 3 was compared to CIN 3 of Group 1.