Organ Histopathology scores of observation (mean) per each group Groups
A B C D Kruskal-Wallis Test for global comparison of organ lesions among groups
Asymptotic Significant (p<0.05)
Liver Activated kupffer cells 0 0 0 0 0.39
Sinusodial widening 0 0 0 0 0.39
Cytoplasmic vacuolation 0 0 0.33 ± 0.21 0.50 ± 0.22 0.39
Karyorrlysis 0 0 0 0 1.00
Karyorrhexis 0 0 0 0 1.00
Mean score 0 0 0.17 ± 0.04 0.17 ± 0.04 0.39
Kidney Granular cast 0 0 0  0.17± 0.06 0.39
Cellular cast 0 0 0 0 1.00
Protein cast 0 0 0 0 1.00
Pycnotic cell 0 0 0.33 ± 0.21 0.50 ± 0.22 0.39
Hydropic degeneration 0 0 0 0 1.00
Mean score 0 0 0.07 ± 0.04 0.13 ± 0.06 0.39
Hydropic degeneration 0 0 0 0 1.00
Mean score 0 0 0.07 ± 0.04 0.13 ± 0.06 0.39
Group A: Normal diet (Control); Group B: Normal diet+70 mg/kg extract; Group C: Normal diet + 140 mg/kg extract; Group D: Normal diet + 210 mg/kg extract.
Table 5: Lesion scores of kidney and liver for all groups analyzed using Kruskal-Wallis test (Subchronic Toxicity).