Segment with obvious Retinal pathology
Phospho-TAK1 expression TAK1 expression Clinical diagnosis Patient
Not detected +++ Blind, painful eye (clinical diagnosis unknown) 1
Not detected +++ Blind eye, Choroidal hemorrhage following traumatic perforation 2
+ +++ Blind eye, Neovascular glaucoma following CRVO* 3
Not detected +++ Blind eye, Infectious choroiditis 4
Not detected +++ Blind eye, Glaucoma and CRVO* 5
Segment with non-obvious Retinal pathology
Phsopho-TAK1 TAK1 expression Pathology Clinical diagnosis Patient
+++ +++ Retinoblastoma 6
++ +++ Orbital lymphangioma 7
+++ +++ Retinoblastoma 8
+++ +++ Invasive BCC** 9
+++ +++ Malignant melanoma 10
*CRVO = central retinal vein occlusion
** BCC = Invasive Basal Cell Carcinoma
Table 2: TAK1 and phospho-TAK1 expression in retinal specimens.