| Group |
Dose(ug/Kg) |
Time/day |
ALT(IU/L) |
AST(IU/l) |
ALP |
Totalprotein(mg/min) |
| GroupI(Control): |
|
|
42.56 ±2.26 |
74.25 ±1.62 |
115.14 ±1.86 |
8.33 ±1.2 |
| Group II |
3ug/kg |
2wks |
71.34 ±1.13* |
98.68 ±1.53* |
122.1 ±1.8* |
7.1 ±0.24* |
| 3ug/kg |
4wks |
95.15 ±0.75** |
162.83 ±2.7** |
137.74 ±1.62** |
6.82 ±0.81** |
| Washout |
2wkswashout |
86.74 ±2.13** |
150.72 ±1.62** |
132.8 ±2.92** |
7.62 ±0.36* |
| Group III |
60ug/kg |
2wks |
121.19 ±1.85*** |
213.72 ±1.6*,* |
165.82 ±2.04***, |
5.58 ±1.12** |
| 60ug/kg |
4wks |
265.56 ±1.51*** |
360.21 ±1.63*** |
193.42 ±1.91*** |
4.35 ±0.67*** |
| Washout |
2wkswashout |
242.38 ±1.43*** |
341.3 ±1.55*** |
174.87 ±1.84*** |
5.13 ±0.85*** |
| Valuesareexpressedasmean ±SEM,*p<0.05;**p<0.01;***p<0.001v/sControl;MGDatawereanalyzedbyusingonewayANNOVA. |
|
