GroupTime/day Mean ±SD Pvalue Significance GroupI(Control):       GroupII2wks 19.79 ±5.0022 - - 4wks 22.31 ±4.1020 - - 2wkswashout 18.09 ±1.0210 - - GroupIII2wks 29.46 ±0.7010 0.001 s 4wks 36.32 ±3.4310 0.002 s 2wkswashout 30.76 ±5.1510 0.001 s SD: StandardDeviation;S: SignificantatP<0.05.

Table 2: Showing the mean area % of caspase-3 expression, SD and P value in in groups I, II and III. Group III compared with group II.