Preparation Method Fractions EE % Mean particle size (nm) Polydispersity FT AMGE 11.13±0.43 145.6±3.9 0.346±0.005 NMGE 10.03±0.38 138.7±4.1 0.317±0.002 TFE AMGE 13.26±0.34 125.1±3.4 0.333±0.004 NMGE 12.40±0.22 129.1±3.8 0.301±0.004 EI AMGE 16.83±0.42 114.8±4.0 0.367±0.005 NMGE 15.30±0.31 116.1±2.0 0.205±0.003

Table 2: Effect of different preparation methods and loading capacity on particle size distribution of AMGE and NMGE liposomes (EE%: percentage of encapsulation efficiency)