Time  linear approximate equation P Not filtered Filtered Slope Intercept 0-24h y=0.22x-0.21 (0.96) y=0.18x+0.13 (1.0) 0.207* 0.684* 0-39h y=0.33x-1.2 (0.92) y=0.16x+0.39 (0.97) 0.00868** —*** 0-48h y=0.39x-1.9 (0.94) y=0.14x+0.57 (0.97) 0.000289** —***

Table 2: The comparison of linear approximate equation on the enzymatic reaction until each time () shows coefficient of correlation, * p>0.05; not significant, ** p<0.05; significant, *** When significant difference was not confirmed in slope, the intercept was not examined.