Figure 6: Loss of the ISO effect on rAAV expression in calcineurin Aβ- nullizygous mice. rAAV-CMV-hGH vector was injected into the heart muscle of calcineurin Aβ nullizygous mice with β-receptor stimulation (ISO acute) or β-receptor down regulation (ISO chronic), or wild type control mice. The meanąSEM serum hGH concentration is shown. *p<0.05 (n=6) vs. CNAβ-/- mice, N.S.: not significant.