Figure 5: En face quantification of aortic atherosclerotic lesions. 1. PBS (n=5); 2. HDAd-0 (n=4); 3. HDAd-P-E3 (n=3); 4. HDAd-PW-E3 (n=5); 5. HDAd-PWL-E3 (n=4); 6. HDAd-AI-E3 (n=2); 7. HDAd-AIW-E3 (n=5); 8. HDAd-AIWL-E3 (n=4); 9. HDAd-E-E3 (n=3); 10. HDAd-EW-E3 (n=4); 11. HDAd-gE3 (n=5), 12. HDAd-gE3 (n=5). HDAd-0 was on pΔ28 backbone and HDAd-gE3 was on pΔ21 backbone. All other HDAd vectors were on C4HSU backbone. *p<0.05 vs. PBS, **p<0.01 vs. HDAd-gE3. Mann-Whitney Rank Sum Test was used. Median, 25th percentile and 75th percentile values are indicated