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Figure 4: Immune response status of aortas with augmented hPRDX6 is
unremarkable. A. shows a QRT-PCR analysis of IL-7 expression, a Th1 response cytokine. MRNA was isolated from the aortas of 3 members of each group. Note that IL-12 levels were unchanged in hPRDX6-HCD treated animals than Neo-HCD treated. B. shows a similar QRT-PCR analysis of IL-7 expression, another Th1 response cytokine. Again, no significant change was observed. C. shows a QRT-PCR analysis of IL-4 expression, a Th2 response cytokine. Note that IL-4 levels were unchanged among the three animal groups. D. shows a QRT-PCR analysis of IL-10 expression, another Th2 response cytokine. Note, that IL-10 levels were significantly lower in hPRDX6-HCD treated animals than Neo-HCD treated. |