Figure 4: Immune response status of aortas with augmented hPRDX6 is unremarkable.
A.
shows a QRT-PCR analysis of IL-7 expression, a Th1 response cytokine. MRNA was isolated from the aortas of 3 members of each group. Note that IL-12 levels were unchanged in hPRDX6-HCD treated animals than Neo-HCD treated.
B.
shows a similar QRT-PCR analysis of IL-7 expression, another Th1 response cytokine. Again, no significant change was observed.
C.
shows a QRT-PCR analysis of IL-4 expression, a Th2 response cytokine. Note that IL-4 levels were unchanged among the three animal groups.
D.
shows a QRT-PCR analysis of IL-10 expression, another Th2 response cytokine. Note, that IL-10 levels were significantly lower in hPRDX6-HCD treated animals than Neo-HCD treated.