Figure 1: shows the survival of normal lymphoblastoid cells and those derived from individuals with mono-allelic mutations in the BRCA1 and BRCA2 genes. Two normal cell lines are combined to produce the survival curve and three are combined to produce the data for the BRCA1 and BRCA2 cell survival curves. Error bars represent standard error of the mean of at least three independent experiments. Due to the logarithmic scale used for the Olaparib concentrations (x axis) survival at zero dose is not shown. However, survival was 100%. A concentration of 5μM Olaparib was chosen for all future experiments as representing concentration with minimal toxicity to all cell lines.