| Mammals |
D. melanogaster |
S. cerevisiae |
S. pombe |
Function |
| NIPBL/SCC2 |
Nipped-B |
Scc2 |
Mis4 |
Cohesin loading |
| MAU2/SCC4 |
Mau2 |
Scc4 |
Ssl3 |
Cohesin loading |
| ESCO1 |
Eco/Deco |
Eco1/Ctf7 |
Eso1 |
Cohesion establishment |
| ESCO2 |
San |
| PDS5A |
Pds5 |
Pds5 |
Pds5 |
Cohesion maintenance |
| PDS5B/APRIN |
| WAPL/WAPAL |
Wapl |
Rad61/Wpl1 |
Wpl1 |
Cohesion maintenance |
| SORONIN/CDCA5 |
Dmt (Dalmatian) |
- |
- |
Cohesion maintenance |
| HDAC8 |
- |
Hos1 |
- |
Cohesindacetylase |
| Shugosin1 |
Sse1 |
Esp1 |
|
Protection of centromeric cohesion |
| Separase |
Sse1 |
Esp1 |
Separase |
Cohesin removal |
| Polo like Kinase 1 (PLK1) |
Polo |
Cdc5 |
Plk1 |
Cohesin removal |
|
