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Figure 3: Deadly effects of transgenic expression of DNases in the ovarian cancer cells over-expressing EGFRvIII from ascites and culture were quantified by labeling of the cells with superparamagnetic antibodies against dsDNA followed by measuring relaxivities with NMRS. That followed by separation of the labeled cells with MACS. Lethal effects of transgenic DNases onto the ovarian cancer cells were quantified by labeling with the elemental tagged antibodies for EDXS to yield identical results. Viability of the cells remained unaffected, when the cells were transfected with the vectors coding reversed orientation sequences as compared to the cells not exposed to any vectors at all. |