Loci  (Haplotypes) Haplotypes  % proportion Total n°
*1/*1 *1/*2 *2/*1 *2/*2
ADA1/ADA2 Colon cancer 71.7% 20.7% 7.1% 0.5% 198
Endometrium cancer 66.4% 21.4% 10.1% 2.1% 132
Controls 69.7% 22.0% 3.9% 4.3% 316
  Chi square test of independence                    χ2         df         p
Colon cancer vs endometrium cancer       3.088        3        0.378
ODDS RATIO ANALYSIS         
*2/*1 vs other haplotypes/all patients vs controls    OR=2.25  95% CI  1.07-4.80   (p=0.030)
*2/*2 vs other haplotypes/all patients vs controls    OR=0.26  95% CI  0.072-0.868 (p=0.024)
ADA1/ADA6 Colon cancer 20.0% 72.6% 4.7% 2.7% 190
Endometrium cancer 19.5% 68.7% 2.6% 9.2% 136
Controls 17.1% 74.2% 3.4% 5.2% 312
  Chi square test of independence       χ2         df             p
Colon cancer vs endometrium cancer   
All haplotypes                               7.346        3        0.062
ADA2/ADA6 Colon cancer 18.9% 63.5% 7.0% 10.6% 176
Endometrium cancer 13.3% 62.8% 7.6% 16.3% 134
Controls 14.0% 58.3% 6.4% 21.5% 272
  Chi square test of independence                    χ2             df              p
Colon cancer vs endometrium cancer        3.181              3        0.364
ODDS RATIO ANALYSIS  
*2/*2 vs other haplotypes/all patients vs controls   OR=0.56  95% CI  0.354-0.891(p=0.013)
Table 3: Distribution of ADA haplotypes in patients and controls.