1. siRNA is incorporated into HVJ-E . 2. The HN proteins on HVJ-E bind receptor moieties of sialic acid on the membrane of the target cells. 3. The molecules (siRNAs) included in HVJ-E vectors are directly delivered into the target cells via the membrane fusion induced by the F proteins.

Figure 1: Delivery of molecules (siRNAs) into cells using HVJ-E vectors.