Ref. Organ/Tissue Host Target genes Delivery route Dose
[62] transplanted tumor (H1299) BALB/C nude mouse Ku80 intratumor injection day0(1shot) or
day 2, 4(2 shots)
[79] transplanted tumor (HeLa) SCID mouse Rad51 intratumor injection 35 μg,  Day 0, 2, 4
[85] transplanted tumor (B16-F10) Mouse Rad51 intratumor injection 2.5 nmol, day 6,8,10
[89] transplanted tumor (U-118MG) Mouse Eg5 intratumor injection 200 pmol, day7,10,13
[94] transplanted tumor (colon26) Mouse bcl-2 intratumor injection 40 μg/1shot
[97] transplanted tumor(A549) Mouse Nrf2 intratumor injection day 1,2,3
[80] submandibular gland Rat rCLCA(Ca2+-dependent clchannels), CFTR(cystic fibrosis transmembrane conductance regulator) retrograde ductal injection 2 nmol, day 0
[83] submandibular gland Rat CFTR (cystic fibrosis transmembrane conductance regulator) retrograde ductal injection 2 nmol day 0
[81] colon Mouse IL-13 Receptorα2 intrarectal injection  
[82] colon Mouse IRF4 intrarectal injection 100 μg, day-2,1-,0,1
[87] colon Mouse Toll like receptor(TLR)-2 intrarectal injection 1 mg
[86] spinal cord Mouse GlyT1, GlyT2, GlyRα3 spinal cord injection 0.45 pmol
[88] spinal cord Mouse GlyR α3 spinal cord injection 0.45 pmol
[100] spinal cord Mouse Phospholipase C-related but catalytical inactive protein (PRIP) spinal cord injection 0.45 pmol
[92] brain Rat Ca(v)3.2 intrathecal(i.t) injection 9 μg/1shot
[98] brain Mouse CD45 intracerebroventricular (ICV) injection 5 μg
[99] brain Mouse GlyRα3 siRNA intrathecal injection  
[96] dorsal horn Rat NK1 receptor intrathecal injection 45 pmol/1shot, day0
[51] lung Mouse IL-13 Receptorα2 Intratracheal injection 100 μg, day0,2,4,6,8,10, 12, 14, 16, 18, 20, 22
[84] inguinal and popliteal LN cells
(enrich in lymphoblasts)
SJL/J mouse (ex vivo ) orphan nuclear receptor NR4A2 adoptive transfer experimental
autoimmune encephalomyelitis (EAE)
model in irradiated mice/ intraperitoneal injection
of NR4A2 siRNA-treated LN cells
 
[90] spleen Mouse Histamine H4 Receptors tail vein 50 μg
[91] stomach Mouse Stat1 intraperitoneal injection 100 μg
[93] uterus Mouse RCAS1 uterine cavity  
[95] dorsal skin Mouse Int6 subcutaneous injection 40 μg
Table 3: siRNA transfection studies using the HVJ-E (in vivo).