| Combined |
Models of statistical interaction† |
| genotypes* |
Gen-Gen |
Over-Over |
Dom-Dom |
Rec-Rec |
Add-Add |
| AA/BB |
0 |
0 |
0 |
0 |
0 |
| AA/Bb |
1 |
0 |
0 |
0 |
0 |
| AA/bb |
2 |
0 |
0 |
0 |
0 |
| Aa/BB |
3 |
0 |
0 |
0 |
0 |
| Aa/Bb |
4 |
1 |
1 |
0 |
1 |
| Aa/bb |
5 |
0 |
1 |
0 |
2 |
| aa/BB |
6 |
0 |
0 |
0 |
0 |
| aa/Bb |
7 |
0 |
1 |
0 |
2 |
| aa/bb |
8 |
0 |
1 |
1 |
4 |
*A, B: wild type alleles at loci A and B, respectively; a, b: variant alleles at loci
A and B, respectively; †Each column represents a variable coding system that is
equivalent to including an interaction term in a regression analysis having both
SNPs in the specified genetic models; Gen-Gen: Genotypic-Genotypic; Over-
Over: Overdominant-Overdominant; Dom-Dom: Dominant-Dominant; Rec-Rec:
Recessive-Recessive; Add-Add: Additive-Additive; Of these, only the Add-
Add model is actually quantitative (the numbers in the other models represent
categories). |
