| Characteristics |
|
Relative copies of hMSH2 mRNA |
Relative copies of hMLH1 mRNA |
Relative copies of hMSH6 mRNA |
Relative copies of hPMS2 mRNA |
Tumor/ANT MMR mRNA gene expression |
| n |
Tumor |
ANT |
Tumor |
ANT |
Tumor |
ANT |
Tumor |
ANT |
hMSH2 |
hMLH1 |
hMSH6 |
hPMS2 |
| All patients |
31 |
0.0908a,f,ib |
0.03375m |
1.91 |
0.0908 |
1.55 |
1.895 |
0.00339 |
0.0908 |
1.15u |
1.05 |
0.5995 |
0.5995 |
| Gender |
|
|
|
|
|
|
|
|
|
|
|
|
|
| Male |
17 |
0.091b,g |
0.1255 |
1.42 |
1.9 |
1.96 |
17.5 |
0.0118 |
0.03015 |
0.791v |
1.05 |
0.2145 |
0.5475 |
| Female |
14 |
0.0722h |
0.00977 |
3.785 |
2.68 |
1.3p |
1.275 |
0.00156 |
0.001145 |
1.921w |
1.26 |
1.25ia |
1.0195 |
| Tumor Stage |
|
|
|
|
|
|
|
|
|
|
|
|
|
| I |
5 (1WD+4MD) |
0.0276c |
0.0276 |
3.52 |
1.9 |
2.67q |
3.7 |
0.0478 |
0.042 |
0.9739 |
0.773 |
0.626 |
0.847 |
| II |
15 (13MD+1M/PD+1PD) |
0.232d,i |
0.0325 |
4.12 |
2.48 |
1.05r |
1.31 |
0.00232 |
0.000788 |
2.8x |
1.62 |
1.64 |
1.22 |
| III |
11(7MD+2M/PD+2PD) |
0.091j |
0.0577 |
0.952n |
2.64 |
1.05s |
1.84 |
0.00112 |
0.00172 |
0.619 |
0.61 |
0.357 |
0.578 |
| Lymph node metastasis |
|
|
|
|
|
|
|
|
|
|
|
|
|
| No |
19 |
0.091e,k,ic |
0.03375 |
4.12o |
2.48 |
2.27t |
1.275 |
0.00428 |
0.000536 |
2.83y |
1.62 |
1.925 |
2.855 |
| Yes |
12 |
0.07245l |
0.03297 |
0.9445 |
2.53 |
0.848 |
2.3 |
0.000994 |
0.01061 |
0.5215z |
0.587 |
0.2955 |
0.5415 |
Mean age of the patients was 74years; ANT, Adjacent normal tissue; MMR, mismatch repair; WD, well differentiated tumors; MD, moderately differentiated tumors; M/PD,
moderately-poorly differentiated tumors; PD, poorly differentiated tumors. ar=0.574765736, br=0.796820522, cr=0.99204665, dr=0.794450379, er=0.794045972, by Pearson
test; correlation between hMSH2/hPBGD & hMLH1/hPBGD mRNA ratios; fr=-0.008816335, gr= -0.054661116, hr=-0.008369458, ir=-0.066294139, jr=0.893917164, kr=-
0.054872336, lr=0.892161159, by Pearson test; correlation between hMSH2/hPBGD & hMSH6/hPBGD mRNA ratios; mr=0.618906296, by Pearson test; correlation between hMSH2/hPBGD & hPMS2/hPBGD mRNA ratios; nr=0.819228481, or= 0.81809858, Pearson test; correlation between hMLH1/hPBGD & hPMS2/hPBGD mRNA ratios; pr=0.82653886, qr=0.99792412, rr=0.96520875, sr= -0.0030656, tr= 0.63185688, by Pearson test; correlation between hMSH6/hPBGD & hPMS2/hPBGD mRNA ratios; ur=0.999389, vr=0.999937, wr=-0.00904, xr= 0.999477, yr= 0.999475, by Pearson test; correlation between hMSH2 & hPMS2 mRNA ratios of Tumor/ANT; zr=0.644378, by
Pearson test; correlation between hMSH2 & hMSH6 mRNA ratios of Tumor/ANT; Iar= 0.992066865, by Pearson test; correlation between hMSH6 & hPMS2 mRNA ratios
of Tumor/ANT; ibP= 0.037994, icP=0.03214, by Student’s test, correlation between hMSH2/hPBGD ratios of Tumor/ANT
|
