| SNP |
Locus /
Gene |
Chm |
Ma/Min
Allele |
MAF1
(%) |
MAF2
(%) |
RR1 |
RR2 |
Encodes / function |
| rs1562430 |
8q24 |
8 |
T/C |
42% |
- |
0.85 |
- |
- |
| rs909116 |
LSP1 |
11 |
T/C |
47% |
- |
0.85 |
- |
Intracellular F-actin binding protein |
| rs10995190 |
ZNF365 |
10 |
G/A |
15% |
16% |
0.86 |
0.86 |
Zinc finger protein 365 |
| rs1156287 |
COX11 |
17 |
A/G |
29% |
- |
0.91 |
- |
Catalyzes the electron transfer from reduced cytochrome c to oxygen |
| rs2380205* |
10q |
10 |
C/T |
46% |
- |
0.94 |
- |
On block with ANKRD16 (encoding ankyrin repeat domain 16) and FBXO18 (encoding the F-box protein, helicase 18) [7] |
| rs704010 |
ZMIZ1 |
10 |
G/A |
39% |
38% |
1.07 |
1.08 |
Member of the PIAS (protein inhibitor of activated STAT) family |
| rs11249433 |
1p11.2 |
1 |
A/G |
42% |
40% |
1.08 |
1.09 |
- |
| rs1011970 |
CDKN2A |
9 |
G/T |
17% |
17% |
1.09 |
1.06 |
Cyclin-dependent kinase inhibitors |
| rs9790879 |
5p12 |
5 |
T/C |
40% |
- |
1.10 |
- |
- |
| rs10931936 |
CASP8 |
2 |
C/T |
26% |
- |
1.14 |
- |
Member of the cysteine-aspartic acid protease (caspase) family |
| rs8009944 |
RAD51L1 |
14 |
A/C |
25% |
- |
1.14 |
- |
Member of the RAD51 family |
| rs614367 |
11q13 |
11 |
C/T |
15% |
15% |
1.15 |
1.21 |
Plausible flanking genes [7]: MYEOV, CCND1, ORAOV1,
FGF19, FGF4 and FGF3 |
| rs4973768 |
SLC4A7 |
3 |
C/T |
47% |
47% |
1.16 |
1.10 |
A sodium bicarbonate co-transporter |
| rs13387042 |
2q35 |
2 |
A/G |
49% |
51% |
1.21 |
1.14 |
- |
| rs889312 |
MAP3K |
5 |
A/C |
28% |
28% |
1.22 |
1.12 |
A serine / threonine kinase |
| rs3757318 |
ESR1 |
6 |
G/A |
7% |
7% |
1.30 |
1.16 |
An estrogen receptor |
| rs3803662 |
TOX3 |
16 |
G/A |
26% |
26% |
1.30 |
1.24 |
Protein containing HMG-box |
| rs2981579 |
FGFR2 |
10 |
G/A |
42% |
40% |
1.43 |
1.27 |
Member of the fibroblast growth factor receptor family |
