1 A chronic cough in patients with no symptoms or objective evidence of variable airflow obstruction
2 Normal airway hyper-responsiveness (provocation concentration of methacholin e producing a 20% decrease in forced expiratory volume in 1 minute (FEV1), PC 20 greater than 16 mg/mL).
3 Sputum eosinophilia (An acceped upper cut-off level of greater than 3% nonsquamous sputum eosinophils) †
†This is outside the 90th percentile for normal patients (1.1%).
Table 5: Diagnostic criteria for non-asthmatic eosinophilic bronchiis (must fulfil all criteria 1–3)