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Figure 1: The association of the numerical data of cystic fibrosis patients with the insertion of 134 bases polymorphism. A. SpO2 in patients without taking into account CFTR mutations (p-value = 0.034). B. SpO2 in patients without CFTR mutations identified (p-value = 0.034). C. Kanga score in patients without CFTR mutations identified (p-value = 0.008). D. Haplotype analysis in patients without taking into account CFTR mutations considering the FVC (p-value = 0.028); 0 ≠ 1,2 and 4. CFTR= Cystic Fibrosis Transmembrane Regulator; +, represents the polymorphism presence; FVC, Forced Ventilatory Capacity; 0, only wild-type alleles; 1, insertion of 134 bases with wild-type + 315 bases deletion with one deleted allele; 2, insertion of 134 bases with wild-type + 315 bases deletion with two deleted alleles; 3, insertion of 134 bases with one inserted allele + 315 bases deletion with wild alleles; 4, insertion of 134 bases with one inserted allele + 315 bases deletion with one/two deleted alleles. For A, B and C, the Mann-Whitney test was performed. For D, the Kruskall-Wallis test was performed. |