Figure 1: Pedigree of case-1 family and kayotype of case child and father. Pedigree representing father (I-1) with kayotype [45,XY,rob(13;14)(q10;q10)] and proband (arrow) (II-3) with karyotype [46,XY,rob(13;14)(q10;q10),+21] are shown as dark square. Mother (I-2) and daughter (II-2) with normal kayotype (46,XX) are shown as circles. The daughter (II-1) expired after birth is shown as crossed square. A: Karyotype of the proband, arrowhead showing [rob t(13;14)], the two arrows show single chromosome 14 and trisomy 21 respectively. B: Karyotype of the father, arrowhead showing [rob t(13;14)] and arrow shows single chromosome 14.