| |
Position(s) in protease |
| Protease inhibitors |
Critical substitutions |
Additional substitutions |
| Saquinavir |
48, 90 |
10, 36, 63, 71 |
| Ritonavir |
82, 84 |
20, 36, 46, 54, 63, 71, 90 |
| Indinavir |
46, 82 |
10, 20, 24, 32, 54, 63, 71, 84, 90 |
| Nelfinavir |
30 |
46, 63, 71, 88, 90 |
| Amprenavir |
50 |
10, 46, 47 |
|
