Interactions present in all 14 Indinavir PDB complex structures presently available in HIV-PDI Interactions present in all 10 Nelfinavir PDB complex structures presently available in HIV-PDI Interactions present in all 14 Saquinavir PDB complex structures presently available in HIV-PDI
Residue Number
ALA 28A
ALA 28B
ARG 8A
ASP 25A
ASP 25B
ASP 29A
ASP 29B
ASP 30A
ASP 30B
GLY 27A
GLY 27B
GLY 48A
GLY 48B
GLY 49A
GLY 49B
LEU 23A
LEU 23B
PRO 81A
PRO 81B
Residue Number
ALA 28A
ALA 28B
ARG 8B
ASP 25A
ASP 25B
ASP 29A
GLY 27A
GLY 27B
GLY 49B
ILE 47A
ILE 47B
ILE 50A
ILE 50B
LEU 23A
LEU 23B
PRO 81A
PRO 81B
VAL 32A
VAL 32B
Residue Number
ALA 28A
ASP 25A
ASP 29A
ASP 30A
GLY 27A
GLY 49A
ILE 47A
LEU 23A
PRO 81A
Table 8: Critical residues involved in ARV interactions and characterized in the crystal HIV-1 proteases from HIV-PDI database. Critical residues involved in ARV interactions and characterized in the crystal HIV-1 proteases from HIV-PDI database in complex with indinavir, nelfinavir, and saquinavir, respectively.