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Figure 1: Effect of isoniazid (INH) on liver histopathological changes in mouse (HE × 100). The mouse were ig given INH 99 mg·kg-1·d-1 or vehicle once per day for 1 d, 3 d, 5 d, 7 d, 2 w, 3 w, 4 w respectively and were scarificed. The liver tissue samples were collected from the control (A) group, or INH-treated for 1 d (B), 3d (C), 5 d (D), 7 d (E), 2 w (F), 3 w (G), 4 w (H) group respectively. |