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Figure 3: Tumor growth inhibition by PXL, Dex-PXL, FA-adsorbed Dex-PXL, and Dex-PXL-FA (covalent). Nude mice with KB xenograft tumors were treated with a series of three i.v. injections (given every other day, as indicated by the arrow heads) of Dex-PXL containing 10 mg/kg PXL (arrow head showing the day of administration). ***means p < 0.001. |