Sr. no. Solvent used   Solubility in each solvent (mg/ml) Pure LVS F1 F2 F3 1. Distilled water 0.005 ± 0.01 0.092 ± 0.02 0.090 ± 0.05 0.081 ± 0.01 2. Acid buffer  (PH 1.2) 0.007 ± 0.03 0.148 ± 0.04 0.131 ± 0.03 0.097 ± 0.03 3. Phosphate buffer (PH 7.4) 0.008 ± 0.02 0.176 ± 0.01 0.173 ± 0.01 0.134 ± 0.04 SD is standard deviation for n = 3 observations

Table 2: Solubility determination of all formulations & pure drug in each solvent.