Formula Preparation Technique Process
yield
(%w/w)
Loading capacity
(%w/w)
Association efficiency
(%w/w)
Particle
Size
(nm)
N1 Precipitation 34.65±(3.06) 3.6±(0.03) 92.3±(4.25) 320±(4.58)
N2 39.28±(3.59) 3.7±(0.05) 35.1±(1.58) 480±(6.39)
N3 56.12±(2.59) 35.20±(3.49) 64.89±(2.48) 390±(5.20)
N4 27.80±(3.68) 6.7±(0.09) 82.1±(2.33) 150±(3.54)
N5 19.24±(1.49) 5.1±(0.11) 70.1±(3.25) 100±(2.38)
N6 26.93±(3.40) 45.92±(3.77) 72.43±(3.04) 220±(3.92)
N7 Ionic-gelation 22.67±(3.36) - - 161±(2.25)
N8 61.38±(2.57) 58.65±(3.59) 93.43±(4.85) 172±(3.69)
N9 48.35±(3.90) 29.73±(1.22) 84.32±(2.75) 323±(5.19)
N10 32.02±(4.75) 23.20±(2.56) 62.50±(3.66) 438±(7.22)
Table 2: Process Yield, HSA Loading Capacity (%LC), Association Efficiency (%AE) and Particle Size of the Prepared Chitosan Nanoparticles (values are mean ± SD, n = 3).