Groups of rats that were administered suspensions of particles with diameters:

10 nm

50 nm

1 μm

Controls (water)

Iron content (mg/kg raw tissue)

200 ± 9*

257 ± 8*+

258 ± 15*+

141 ± 5+

Difference between group administered magnetite and controls

59 ± 10

116 ± 9+

117 ± 16+

-

*designates values that are statistically significantly different from control value;
+ same from the value for the group of rats administered 10-nm particles (P<0.01 by Student’s t-test)
Table 2: Iron content of rat lung tissue 24 hours after intratracheal instillation of 2 mg of magnetite particles of various sizes or distilled water (X±s.e.)