Gene Expression

NM 110

NM 111

NM 300

NM 400

NM 402

NRCWE 002

IL6

-200%

-50%

-200%

0

0

0

IL10

+75%

0

0

0

+50%

+200%

C3

-50%

-75%

-75%

-50%

-75%

0

CXCL2

+200%

0

0

0

0

0

TNF-α

0

0

0

0

0

0

Fas ligand

0

0

0

0

0

0

ICAM-1

0

0

0

0

0

0

Albumin

0

0

0

0

0

0

Table 2: mRNA expression of inflammatory cytokines and receptors, FasL and albumin in C57/BL6 mice liver. The animals were exposed to 100 μl of 128 μg/ml of panel of nanomaterials for 6 hr by injection via the lateral tail vein. mRNA expression was analysed by real time PCR with B2m utilised as an endogenous control.