Figure 5: Vasomotion of the coronary arteries treated with either nanotechnologies or stent Panel. (a) Represents vasomotor response of coronaries to infusion of acetylcholine (Ach) and nitroglycerine (NTG). The nitroglycerine application (100 μg orally) has been following intravascular infusion of acetylcholine through a microcatheter at increasing doses up to 10-8, 10-7, 10-6 M with a washout period of at least five minutes between each dose. The figure demonstrates the more pronounced vasoreactive response of the arteries in case of the nano-application. Panel (b) shows cumulative frequency of mean lumen diameter after infusion of acetylcholine at 120, 420 and 720 seconds, and nitroglycerine – at 840 seconds. The figure underlines the higher level of the vessel wall reactivity in groups utilizing nanotechnologies if compare with stenting. Asterisk marks p value for the difference between nano-groups and stenting control.