Formulation Cmax [µg/mL] p* to Cntr Ratio Cmax Form./Control AUC0-6h [µg ∙ h/mL] p to Cntr Ratio AUC0-6h Form./Control
Control 0.18 ± 0.02 - 0.97 ± 0.08 -
BR-DIM 0.22 ± 0.02 p=0.207 1.22 1.05 ± 0.05 p=0.429 1.08
F127-DIM 3.08 ± 0.17 p<0.0001 17.11 7.06 ± 0.93 p=0.0006 7.28
*- p-values calculated by two-tailed t-test
Table 1: Cmax and AUC0-6h values calculated for the animals treated with Control (non-formulated crystalline DIM), BioResponse DIM (BR-DIM), and F127-DIM formulation (F127-DIM).