Group Operative measure Duration* Number of animals I 1 mg/kg BW MagnaDrug mitoxantrone** in a magnetic field Once on one day 30 min 6 II 1 mg/kg BW MagnaDrug mitoxantrone** without a magnet 30 min 6 III 1mg/kgBW mitoxantrone** without a magnetic field 30 min 6 IV 1 mg/kg BW MagnaDrug mitoxantrone** 1st day 30 min 2nd day 30 min 6 V 1 mg/kg BW MagnaDrug mitoxantrone** without a magnet 1st day 30 min 6 VI 1mg/kg BW mitoxantrone** without a magnetic field 1st day 30 min 6 *Duration: Duration of exposure to the magnetic field ** Slow intravenous injection over 5 minutes Total number=Σ 36

Table 1: Study groups in the biodistribution.