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Figure 3: Characterization of Curc and TAT-peptide binding reactions
on NL surface. NL were functionalized with Curc and TAT-peptide and purified as described in the text. A) Representative mass spectrometry spectrum of Curc-PEG-lipid, the product of the reaction between Curc and azido-PEG-lipid containing NL; B) Representative fluorescence spectra of TAT-peptide before (red) and after (black) conjugation to maleimide containing NL (λex 280 nm). Curc=curcumin-derivative; NL=nanoliposomes. |