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Figure 4: TAT-Curc-NL binding to Aβ fibrils. Surface Plasmon Resonance sensorgrams resulting from the “global” fitting of the curves obtained from the interaction between Aβ fibrils immobilized on a gold sensor surface and A) not functionalized NL or B) TAT-Curc-NL. NL were flowed in solution at total lipids concentrations of 2, 6, 12 μM for 5 min at 30 μL/min. |