Timing of Homeopathic Medicine Dose Relative to Experimentally-Induced Injury Impact after 1 hour on Injury-Related Edema Compared with Saline Control Treatment 60 minutes before injury induction +14.6%* Simultaneously with injury induction +3.57% 30 minutes after injury induction -13.63%** * p<0.05 **p<0.01 Note: Experimental acute injury = carrageenan-induced paw edema. Verum medicine and saline control treatments were also given by injection

Table 1: Timing of intervention interacts with host state: bidirectional effects of a combination mineral homeopathic medicine dose relative to time of treatment versus time of experimental injury in an animal model of paw edema (N=307 rats). Data from first hour post-dose, after Figure 1, Bertani et al. [74].