Parameter Methocel E15 Blank Film Methocel E15 + BSA nanoemulsion CMCs Blank Film CMCs 8% + BSA nanoemulsion
pH 7.10 ± 0.02 6.88 ± 0.02 8.55 ± 0.02 7.45 ± 0.03
Viscosity (cps)* 875.00 ± 0.00 1206.67 ± 2.89 520.00 ± 0.00 842.67 ± 2.89
Thickness (mm) 0.052 ± 0.005 0.093 ± 0.004 0.049 ± 0.004 0.099 ± 0.005
Weight Variance (mg) 54.70  ± 0.20 81.90 ± 0.40 55.27 ± 0.25 84.13 ± 0.12
Folding Endurance (times) > 300 > 300 > 300 > 300
Disintegration Time (seconds) 59.33 ± 1.53 83.67 ± 1.53 14.67 ± 3.06 32.67 ± 1.53
Dissolution Time (seconds) 155.00 ± 2.65 184.67 ± 2.52 92.00 ± 1.00 124.67 ± 2.52
Tear Resistance (N) 16.10 ± 1.17 4.47 ± 0.51 10.55 ± 1.69 6.71 ± 0.42
Tensile Strength (MPa) 57.23 ± 4.18 12.23 ± 1.40 38.64 ± 5.72 18.35 ± 0.60
%  Elongation 20.85 ± 3.24 21.75 ± 5.24 32.87 ± 3.22 34.23 ± 2.00
Elasticity Modulus (MPa) 1284.00 ± 86.55 285.82 ± 23.95 674.84 ± 67.65 241.77 ± 55.42
Data is shown as mean + standard deviation, n=3
* using Brookfield DV-I Viscometer (S28 spindle and 100 rpm in room temperature)
Table 2: Influence of film-forming polymers on the film characteristics.