Figure 7: Analysis of uptake mechanisms using different inhibitors in
A549 cells in the presence of serum.
Cells were pretreated with various
inhibitors, Genistein, Filipin and Chlorpromazine, for 30 min, followed
by 2h exposure to SiO2 NP. Given are means ± SEM of 2 independent
experiments, each with 3 replicates. The normalized fluorescence (%
uptake) were calculated by dividing the SiO2 NP fluoresence in the presence
of inhibitor by the fluorescence of controls without inhibitors.