Identification
code |
Nanoparticle formulation constituents |
Disperse nanoparticle lipid phasea |
Dispersing aqueous phaseb |
Tristearin |
Mygliol |
Cardiogreen |
Rhodamine |
Poloxamer 188 |
Polysorbate 80 |
#SLN |
100.0 |
n.p. |
n.p. |
n.p. |
2.5 |
n.p. |
#SLN-P80 |
100.0 |
n.p. |
n.p. |
n.p. |
2.5 |
1.0 |
#NLC |
66.6 |
33.3 |
n.p. |
n.p. |
2.5 |
n.p. |
#NLC-P80 |
66.6 |
33.3 |
n.p. |
n.p. |
2.5 |
1.0 |
#SLN-RH |
99.6 |
n.p. |
n.p. |
0.4 |
2.5 |
n.p. |
#SLN-P80-RO |
99.6 |
n.p. |
n.p. |
0.4 |
2.5 |
1.0 |
#NLC-RH |
66.6 |
33.3 |
n.p. |
0.4 |
2.5 |
n.p. |
#NLC-P80-RH |
66.6 |
33.3 |
n.p. |
0.4 |
2.5 |
1.0 |
#SLN-CG |
99.6 |
n.p. |
0.4 |
n.p. |
2.5 |
n.p. |
#SLN-P80-CG |
99.6 |
n.p. |
0.4 |
n.p. |
2.5 |
1.0 |
|
n.p.: not present;
athe values are expressed as weight percentage with respect to the lipid phase constituting the nanoparticle matrix;
bthe values are expressed as weight percentage with respect to the dispersing aqueous phase; in all the batches the total weight of the disperse lipid phase is 5% w/w with
respect to the whole weight of the dispersion |
Table 1: Identification codes and chemical composition of the nanoparticles used in the present study. |