Identification
code
Nanoparticle formulation constituents
Disperse nanoparticle lipid phasea Dispersing aqueous phaseb
Tristearin Mygliol Cardiogreen Rhodamine Poloxamer 188 Polysorbate 80
#SLN 100.0 n.p. n.p. n.p. 2.5 n.p.
#SLN-P80 100.0 n.p. n.p. n.p. 2.5 1.0
#NLC 66.6 33.3 n.p. n.p. 2.5 n.p.
#NLC-P80 66.6 33.3 n.p. n.p. 2.5 1.0
#SLN-RH 99.6 n.p. n.p. 0.4 2.5 n.p.
#SLN-P80-RO 99.6 n.p. n.p. 0.4 2.5 1.0
#NLC-RH 66.6 33.3 n.p. 0.4 2.5 n.p.
#NLC-P80-RH 66.6 33.3 n.p. 0.4 2.5 1.0
#SLN-CG 99.6 n.p. 0.4 n.p. 2.5 n.p.
#SLN-P80-CG 99.6 n.p. 0.4 n.p. 2.5 1.0
n.p.: not present;
athe values are expressed as weight percentage with respect to the lipid phase constituting the nanoparticle matrix;
bthe values are expressed as weight percentage with respect to the dispersing aqueous phase; in all the batches the total weight of the disperse lipid phase is 5% w/w with
respect to the whole weight of the dispersion
Table 1: Identification codes and chemical composition of the nanoparticles used in the present study.