| Parameters (Units) |
MEAN ± SD
(un-transformed Data) |
| Taxotere |
NDLS |
| Tmax (h) |
1.000 |
1.000 |
| Cmax (µg/mL) |
5.03 ± 2.47 |
7.03 ± 230 |
| AUCo-t(µg.h/mL) |
5.73 ± 4.50 |
6.01 ± 2.65 |
| AUC0-∞(µg.h/mL) |
6.13 ± 4.56 |
6.41 ± 2.78 |
| λz (1/h) |
0.059-1.041 |
0.055 ± .042 |
| T1/2 (h) |
21.24 ± 26.1 |
21.28 ± 18.1 |
| Vz (L/m2) |
434 ± 497 |
356 ± 239 |
|
| aTmax is represented in median value |
| Table 3: The Pharmacokinetic Parameters of Docetaxel for NDLS and Taxotere® (N=28 Patients). |
