Note: PC: L-α-Phosphatidylcholine; Chol: Cholesterol; DDAB:
Didecyldimethylammonium bromide; DPPC: 1,2-Dipalmitoyl-sn-glycero-3-
phosphocholine; DCP: dicetyl phosphate; DSPC: 1, 2-Distearoyl-sn-glycero-3-
phosphocholine.
Table 1: Liposomal β-Glucan: particle size, encapsulation efficiency and
polydispersity index: Particle size, polydispersity index (P.I.) and encapsulation
efficiency of β-Glucan into liposomes. Particle size and polydispersity index (P.I.)
of liposomes were determined by photon correlation spectroscopy with the use of
Submicron Particle Sizer. All liposomes preparations were analyzed and Gaussian
distributions were recorded. P.I., gives the measurement of homogeneity of
dispersion, ranging from 0.0 (homogenous) to 1.0 (heterogeneous). Encapsulation
efficiency was determined as the percentage of β -Glucan incorporated into
liposomes relative to initial total amount of drug in solution. Results are given as
means ± S.E.M. of three separated experiments in triplicate. ****P<0.0001. |
